This cofactor is required for the remethylation of homocysteine, SAM-e, and glutathione, which aids in the formation of important neurotransmitters, the breakdown of vitamin B12 and B6, healthy hormone production, liver detoxification, and genetic regulation.
If the re-conversion of homocysteine into L-methionine is sidestepped, risk factors for arteriosclerotic vascular disease, anemia, venous thrombosis, coronoary heart disease, and cancer increase. Methionine helps with depression, inflammation, and the conversion of estradiol (E2) into estriol (E3). Methionine can be converted into SAM-e (s-adenosylmethionine), which has anti-inflammatory properties, strengthens the immune system, and helps produce serotonin, melatonin, and dopamine.
Even though there are variations of the mutation, all deficiencies in MTHFR can cause disastrous developmental issues, such as autism, dementia, fibromyalgia, chronic migraines, nerve pain, issues with pregnancy, and schizophrenia. According to research, more than half the general population has some type of MTHFR mutation. Even though you can’t swap out a defective gene, you can help the gene work better with the right nutritional intervention, vitamin supplements, and detoxification therapies.
Luckily, with a simple blood test, you can find out if you have the MTHFR mutation. Whether your family has a history or not, individuals can discover if they harbor this common genetic variant, which causes abnormal absorption of folate. Folate is responsible for cell growth, utilization of proteins, and red blood cell maturation. There are over 50 variations, but only a select few are of concern. As the person ages, undiagnosed cases of MTHFR can become much worse, so it is important to get tested early and practice prevention.
Using other forms of functional medicine as our guide, the Salerno Center for Complementary Medicine offers unique, customizable IV therapy vitamins for MTHFR, which include metholated folate, glutathione, and other important nutrients for remethylation. Depending on the treatment plan and personal needs, this broad spectrum IV mixture can be administered once or twice a week for several months at a time for convenient, absorbable, targeted care.
Besides MTHFR testing, other areas of evaluation include metal toxicity, thyroid, vitamin D, adrenals, environmental/food sensitivity panels, organic acids, and viral antibodies.